/* GLP-1 Atlas — tasarım sistemi.
   Referans yayını tonu: kâğıt sıcaklığında zemin, okumak için serif gövde,
   arayüz için sans. Tek vurgu rengi; her göründüğünde bir şey söylüyor. */

:root {
  --paper:      #faf9f7;
  --paper-2:    #f2f0ec;
  --card:       #ffffff;
  --ink:        #16181d;
  --ink-soft:   #4a4f5a;
  /* Denetimde ölçüldü: #767c88 kâğıt zeminde 3,98:1 veriyordu ve künye
     satırı ile tablo başlıkları küçük punto — AA eşiği 4,5. Bu değer en zor
     zeminde (--paper-2) 4,93. */
  --ink-faint:  #616874;
  --rule:       #e3e0da;
  --rule-soft:  #eeebe5;
  --accent:     #0f6a5b;
  --accent-ink: #0b5245;
  --accent-bg:  #e8f2ef;
  --warn:       #9a4a1c;
  --warn-bg:    #fbeee4;
  --alert:      #a02a24;
  --alert-bg:   #fbeceb;
  --shadow:     0 1px 2px rgba(20,22,28,.05), 0 8px 24px -12px rgba(20,22,28,.14);

  --serif: "Newsreader", ui-serif, Georgia, "Times New Roman", serif;
  --sans:  "Inter", -apple-system, BlinkMacSystemFont, "Segoe UI", Roboto, sans-serif;
  --measure: 34rem;
}

@media (prefers-color-scheme: dark) {
  :root {
    --paper:     #12141a;
    --paper-2:   #171a21;
    --card:      #191c24;
    --ink:       #e9ebf0;
    --ink-soft:  #b0b6c2;
    --ink-faint: #868d9b;
    --rule:      #272b35;
    --rule-soft: #21242c;
    --accent:    #58c4ac;
    --accent-ink:#7fd6c1;
    --accent-bg: #14312c;
    --warn:      #e0a173;
    --warn-bg:   #2e2116;
    --alert:     #ef9089;
    --alert-bg:  #33191a;
    --shadow:    0 1px 2px rgba(0,0,0,.4), 0 10px 30px -14px rgba(0,0,0,.7);
  }
}

*, *::before, *::after { box-sizing: border-box; }

html { -webkit-text-size-adjust: 100%; }

body {
  margin: 0;
  background: var(--paper);
  color: var(--ink);
  font-family: var(--serif);
  font-size: 19px;
  line-height: 1.62;
  font-optical-sizing: auto;
  -webkit-font-smoothing: antialiased;
}

a { color: inherit; }

.wrap { width: min(72rem, calc(100% - 2.5rem)); margin-inline: auto; }
.narrow { width: min(var(--measure), calc(100% - 2.5rem)); }

.skip {
  position: absolute; left: -9999px;
  background: var(--ink); color: var(--paper);
  padding: .7rem 1.1rem; border-radius: 6px; font-family: var(--sans);
}
.skip:focus { left: 1rem; top: 1rem; z-index: 50; }

/* ------------------------------------------------------------ başlık */

.masthead {
  border-bottom: 1px solid var(--rule);
  background: color-mix(in srgb, var(--paper) 88%, transparent);
  backdrop-filter: saturate(1.6) blur(12px);
  position: sticky; top: 0; z-index: 20;
}
.masthead-in {
  display: flex; align-items: center; justify-content: space-between;
  gap: 1.5rem; min-height: 4.25rem; flex-wrap: wrap;
}
.brand {
  display: inline-flex; align-items: center; gap: .6rem;
  text-decoration: none; color: var(--ink);
}
.brand-mark { width: 1.7rem; height: 1.7rem; color: var(--accent); flex: none; }
.brand-text {
  font-family: var(--sans); font-weight: 500; font-size: .98rem;
  letter-spacing: -.015em;
}
.brand-text b { font-weight: 700; }

.nav { display: flex; gap: 1.5rem; font-family: var(--sans); font-size: .875rem; }
.nav a {
  text-decoration: none; color: var(--ink-soft);
  padding-block: .35rem; border-bottom: 2px solid transparent;
  transition: color .15s, border-color .15s;
}
.nav a:hover { color: var(--ink); border-bottom-color: var(--accent); }

/* ------------------------------------------------------------ giriş */

.hero { padding: 5.5rem 0 3.25rem; border-bottom: 1px solid var(--rule-soft); }
.hero h1 {
  font-size: clamp(2.6rem, 6.5vw, 4.4rem);
  line-height: 1.03; letter-spacing: -.032em; font-weight: 500;
  margin: 0 0 1.4rem; text-wrap: balance;
}
.hero-sub {
  font-family: var(--sans); font-size: 1.02rem; line-height: 1.62;
  color: var(--ink-soft); max-width: 40rem; margin: 0;
}

.lead {
  display: block; text-decoration: none; color: inherit;
  margin: 3rem 0 4rem; padding: 2.25rem 2.5rem 2rem;
  background: var(--card); border: 1px solid var(--rule);
  border-radius: 14px; box-shadow: var(--shadow);
  transition: transform .18s ease, box-shadow .18s ease;
}
.lead:hover { transform: translateY(-2px); box-shadow: 0 2px 4px rgba(20,22,28,.06), 0 18px 40px -18px rgba(20,22,28,.28); }
.lead-kicker {
  font-family: var(--sans); font-size: .7rem; font-weight: 600;
  letter-spacing: .13em; text-transform: uppercase; color: var(--accent);
}
.lead h2 {
  font-size: clamp(1.7rem, 3.4vw, 2.4rem); line-height: 1.14;
  letter-spacing: -.022em; font-weight: 500; margin: .7rem 0 .6rem;
  max-width: 26ch; text-wrap: balance;
}
.lead p {
  font-family: var(--sans); font-size: .95rem; color: var(--ink-soft);
  margin: 0 0 1.1rem; max-width: 52ch;
}
.lead-go {
  font-family: var(--sans); font-size: .875rem; font-weight: 600;
  color: var(--accent);
}

/* ------------------------------------------------------------ bloklar */

.block { margin-bottom: 4rem; }
.block-head {
  display: flex; align-items: baseline; gap: 1.25rem;
  padding-bottom: .85rem; margin-bottom: .35rem;
  border-bottom: 2px solid var(--ink); flex-wrap: wrap;
}
.block-head h2 { font-size: 1.35rem; letter-spacing: -.02em; font-weight: 600; margin: 0; }
.block-head h2 a { text-decoration: none; }
.block-head h2 a:hover { color: var(--accent); }
.block-head p { font-family: var(--sans); font-size: .875rem; color: var(--ink-faint); margin: 0; }

.rows { display: grid; }
.row {
  display: grid; grid-template-columns: minmax(0, 20rem) 1fr auto;
  gap: 1.5rem; align-items: baseline;
  padding: 1.15rem .25rem; border-bottom: 1px solid var(--rule-soft);
  text-decoration: none; color: inherit; transition: background .15s;
}
.row:hover { background: var(--paper-2); }
.row-title { font-size: 1.12rem; font-weight: 500; letter-spacing: -.012em; }
.row:hover .row-title { color: var(--accent); }
.row-desc { font-family: var(--sans); font-size: .875rem; color: var(--ink-soft); }
.row-meta { font-family: var(--sans); font-size: .75rem; color: var(--ink-faint); white-space: nowrap; }

/* ------------------------------------------------------------ kartlar */

.section-head { padding: 3.5rem 0 1.5rem; }
.section-head h1 {
  font-size: clamp(2.1rem, 5vw, 3rem); line-height: 1.08;
  letter-spacing: -.028em; font-weight: 500; margin: .5rem 0 .8rem;
}
.card-grid {
  display: grid; gap: 1.25rem; padding-bottom: 4rem;
  grid-template-columns: repeat(auto-fill, minmax(19rem, 1fr));
}
.card {
  display: flex; flex-direction: column; gap: .55rem;
  padding: 1.6rem 1.7rem; background: var(--card);
  border: 1px solid var(--rule); border-radius: 12px;
  text-decoration: none; color: inherit; transition: border-color .15s, transform .18s;
}
.card:hover { border-color: var(--accent); transform: translateY(-2px); }
.card h3 { font-size: 1.22rem; font-weight: 500; letter-spacing: -.018em; margin: 0; }
.card p { font-family: var(--sans); font-size: .875rem; color: var(--ink-soft); margin: 0; flex: 1; }
.card-meta { font-family: var(--sans); font-size: .72rem; color: var(--ink-faint); }

/* ------------------------------------------------------------ yazı */

.crumbs { font-family: var(--sans); font-size: .78rem; color: var(--ink-faint); }
.crumbs a { text-decoration: none; color: var(--accent); }
.crumbs span { margin-inline: .4rem; }

.article { padding-top: 3.25rem; }
.article h1 {
  font-size: clamp(2.2rem, 5.2vw, 3.15rem); line-height: 1.06;
  letter-spacing: -.03em; font-weight: 500; margin: .75rem 0 .9rem;
  text-wrap: balance;
}
.standfirst {
  font-family: var(--sans); font-size: 1.06rem; line-height: 1.6;
  color: var(--ink-soft); margin: 0 0 1.1rem;
}
.byline {
  font-family: var(--sans); font-size: .78rem; color: var(--ink-faint);
  padding-bottom: 1.75rem; margin: 0; border-bottom: 1px solid var(--rule);
}

.prose { padding-bottom: 4.5rem; }
.prose > * { margin-block: 0 1.35rem; }
.prose h2 {
  font-size: 1.62rem; line-height: 1.2; letter-spacing: -.022em;
  font-weight: 600; margin-top: 3.25rem; margin-bottom: 1rem;
}
.prose h3 {
  font-family: var(--sans); font-size: 1.02rem; font-weight: 600;
  letter-spacing: -.008em; margin-top: 2.25rem; margin-bottom: .7rem;
}
.prose a { color: var(--accent-ink); text-underline-offset: 3px; text-decoration-thickness: 1px; }
.prose strong { font-weight: 600; }
.prose ul, .prose ol { padding-left: 1.35rem; }
.prose li { margin-bottom: .55rem; }
.prose li::marker { color: var(--ink-faint); }

.prose blockquote {
  margin-inline: 0; padding: .2rem 0 .2rem 1.5rem;
  border-left: 3px solid var(--accent); color: var(--ink-soft); font-style: italic;
}

/* Öne çıkan sayı — uzun bir açıklamanın tek satırlık özeti. */
.stat {
  display: flex; gap: 1.5rem; align-items: baseline;
  padding: 1.4rem 0; border-block: 1px solid var(--rule);
  margin-block: 2rem;
}
.stat b {
  font-size: 2.6rem; line-height: 1; letter-spacing: -.03em;
  font-weight: 500; color: var(--accent); font-variant-numeric: tabular-nums;
}
.stat span { font-family: var(--sans); font-size: .9rem; color: var(--ink-soft); }

/* Yazının başındaki özet kutusu: acelesi olan buradan çıkabilmeli. */
.keyfacts {
  background: var(--paper-2); border: 1px solid var(--rule);
  border-radius: 12px; padding: 1.6rem 1.8rem; margin-block: 2rem 2.5rem;
}
.keyfacts h2 {
  font-family: var(--sans); font-size: .72rem; font-weight: 600;
  letter-spacing: .12em; text-transform: uppercase; color: var(--ink-faint);
  margin: 0 0 .9rem;
}
.keyfacts ul { margin: 0; padding-left: 1.15rem; }
.keyfacts li { font-size: .96rem; margin-bottom: .5rem; }
.keyfacts li:last-child { margin-bottom: 0; }

.callout {
  border-radius: 12px; padding: 1.3rem 1.5rem; margin-block: 2rem;
  font-family: var(--sans); font-size: .92rem; line-height: 1.58;
  border: 1px solid transparent;
}
.callout p { margin: 0 0 .7rem; }
.callout p:last-child { margin-bottom: 0; }
.callout b { font-weight: 600; }
.callout.note   { background: var(--accent-bg); border-color: color-mix(in srgb, var(--accent) 24%, transparent); }
.callout.note b { color: var(--accent-ink); }
.callout.caution{ background: var(--warn-bg);  border-color: color-mix(in srgb, var(--warn) 26%, transparent); }
.callout.caution b { color: var(--warn); }
.callout.alert  { background: var(--alert-bg); border-color: color-mix(in srgb, var(--alert) 30%, transparent); }
.callout.alert b { color: var(--alert); }

/* Tablolar dar ekranda kendi içinde kaysın, sayfa gövdesi kaymasın. */
.table-scroll { overflow-x: auto; margin-block: 2rem; -webkit-overflow-scrolling: touch; }

/* Gövde metni 34rem'de en iyi okunuyor ama tablo orada sıkışıyor: sütunlar
   kırılıp "0.25 mg / weekly" iki satıra düşüyordu. Geniş ekranda tablo
   ölçünün dışına, iki yana simetrik taşıyor. */
@media (min-width: 62rem) {
  .prose .table-scroll { width: 46rem; margin-left: -6rem; }
}
table {
  border-collapse: collapse; width: 100%; min-width: 30rem;
  font-family: var(--sans); font-size: .875rem;
}
caption {
  text-align: left; font-family: var(--sans); font-size: .78rem;
  color: var(--ink-faint); padding-bottom: .75rem;
}
th, td { padding: .72rem .9rem; text-align: left; vertical-align: top; }
thead th {
  font-size: .72rem; font-weight: 600; letter-spacing: .06em;
  text-transform: uppercase; color: var(--ink-faint);
  border-bottom: 2px solid var(--ink);
}
tbody tr { border-bottom: 1px solid var(--rule-soft); }
tbody tr:hover { background: var(--paper-2); }
td b { font-weight: 600; font-variant-numeric: tabular-nums; }
.num { font-variant-numeric: tabular-nums; white-space: nowrap; }

.reg {
  font-size: .58em; vertical-align: .38em;
  letter-spacing: 0; font-weight: 400;
}

.sources {
  margin-top: 3.5rem; padding-top: 1.75rem; border-top: 1px solid var(--rule);
  font-family: var(--sans); font-size: .84rem; color: var(--ink-soft);
}
.sources h2 {
  font-family: var(--sans); font-size: .72rem; font-weight: 600;
  letter-spacing: .12em; text-transform: uppercase; color: var(--ink-faint);
  margin: 0 0 .9rem;
}
.sources ol { padding-left: 1.2rem; margin: 0; }
.sources li { margin-bottom: .5rem; }

/* Uygulama bağlantısı. Reklam kutusu değil: yazının o noktada anlattığı
   işi yapan bir araç olduğunu söyleyen bir dipnot. */
.toolnote {
  display: flex; gap: 1.1rem; align-items: flex-start;
  margin-block: 2.5rem; padding: 1.3rem 1.5rem;
  border: 1px dashed var(--rule); border-radius: 12px;
  font-family: var(--sans); font-size: .88rem; color: var(--ink-soft);
}
.toolnote svg { width: 1.35rem; height: 1.35rem; color: var(--accent); flex: none; margin-top: .1rem; }
.toolnote p { margin: 0; }
.toolnote a { color: var(--accent-ink); font-weight: 500; }

/* ------------------------------------------------------------ ilgili */

.related { border-top: 1px solid var(--rule); padding: 3rem 0 1rem; background: var(--paper-2); }
.related > h2 {
  width: min(72rem, calc(100% - 2.5rem)); margin: 0 auto 1.5rem;
  font-family: var(--sans); font-size: .72rem; font-weight: 600;
  letter-spacing: .12em; text-transform: uppercase; color: var(--ink-faint);
}
.rel-grid {
  width: min(72rem, calc(100% - 2.5rem)); margin-inline: auto;
  display: grid; gap: 1rem; padding-bottom: 3rem;
  grid-template-columns: repeat(auto-fit, minmax(16rem, 1fr));
}
.rel-card {
  display: flex; flex-direction: column; gap: .4rem;
  padding: 1.3rem 1.4rem; background: var(--card);
  border: 1px solid var(--rule); border-radius: 12px;
  text-decoration: none; color: inherit; transition: border-color .15s;
}
.rel-card:hover { border-color: var(--accent); }
.rel-kicker {
  font-family: var(--sans); font-size: .68rem; font-weight: 600;
  letter-spacing: .12em; text-transform: uppercase; color: var(--ink-faint);
}
.rel-title { font-size: 1.05rem; font-weight: 500; letter-spacing: -.014em; }

/* ------------------------------------------------------------ altlık */

.foot { border-top: 1px solid var(--rule); padding-top: 3.25rem; margin-top: 0; }
.foot-in {
  display: grid; gap: 2.5rem; padding-bottom: 2.75rem;
  grid-template-columns: minmax(0, 2fr) repeat(2, minmax(0, 1fr));
}
.foot-about p {
  font-family: var(--sans); font-size: .85rem; line-height: 1.6;
  color: var(--ink-soft); margin: .8rem 0 0; max-width: 34rem;
}
.foot-col h3 {
  font-family: var(--sans); font-size: .72rem; font-weight: 600;
  letter-spacing: .12em; text-transform: uppercase; color: var(--ink-faint);
  margin: 0 0 .9rem;
}
.foot-col ul { list-style: none; padding: 0; margin: 0; }
.foot-col li { margin-bottom: .5rem; }
.foot-col a {
  font-family: var(--sans); font-size: .875rem; color: var(--ink-soft);
  text-decoration: none;
}
.foot-col a:hover { color: var(--accent); }

.foot-legal { border-top: 1px solid var(--rule-soft); padding: 1.75rem 0 3rem; }
.foot-legal p {
  font-family: var(--sans); font-size: .8rem; line-height: 1.6;
  color: var(--ink-soft); margin: 0 0 .8rem; max-width: 58rem;
}
.foot-legal b { color: var(--ink); font-weight: 600; }
.foot-legal .tm { font-size: .74rem; color: var(--ink-faint); margin-bottom: 0; }

/* ------------------------------------------------------------ dar ekran */

@media (max-width: 720px) {
  body { font-size: 18px; }
  .masthead-in { min-height: auto; padding-block: .9rem; }
  .nav { width: 100%; gap: 1.15rem; overflow-x: auto; padding-bottom: .2rem; }
  .hero { padding: 3.25rem 0 2.25rem; }
  /* Geniş ekranda başlığı iki satıra bölen kırılım, dar ekranda yanlış yere
     düşüyor — orada sarmayı `text-wrap: balance` yapsın. */
  .hero h1 br { display: none; }
  .lead { padding: 1.7rem 1.5rem; margin: 2rem 0 3rem; }
  .row { grid-template-columns: 1fr; gap: .3rem; }
  .row-meta { display: none; }
  .foot-in { grid-template-columns: 1fr; gap: 2rem; }
  .keyfacts, .callout { padding-inline: 1.2rem; }
}

@media (prefers-reduced-motion: reduce) {
  * { transition: none !important; animation: none !important; }
}

/* ------------------------------------------------------------ ilaç kılavuzu */

/* Ana sayfadaki ilaç ızgarası. Kartlardan daha sıkı: burada okunacak bir şey
   yok, tanınacak bir marka adı var — göz sekiz kutuyu tek bakışta taramalı. */
.med-grid {
  display: grid; gap: .8rem; margin-bottom: 1.25rem;
  grid-template-columns: repeat(auto-fill, minmax(11.5rem, 1fr));
}
.med {
  display: flex; flex-direction: column; gap: .1rem;
  padding: 1.1rem 1.2rem; background: var(--card);
  border: 1px solid var(--rule); border-radius: 10px;
  text-decoration: none; color: inherit;
  transition: border-color .15s, transform .18s;
}
.med:hover { border-color: var(--accent); transform: translateY(-2px); }
.med-brand { font-size: 1.14rem; font-weight: 500; letter-spacing: -.015em; }
.med-mol {
  font-family: var(--sans); font-size: .78rem; color: var(--accent);
  font-weight: 500;
}
.med-how { font-family: var(--sans); font-size: .74rem; color: var(--ink-faint); }

.med-compare {
  font-family: var(--sans); font-size: .82rem; color: var(--ink-faint);
  margin: 0 0 .5rem;
}
.med-compare a { color: var(--ink-soft); text-decoration: none; }
.med-compare a:hover { color: var(--accent); text-decoration: underline; }

/* İlaç hub'ındaki alt sayfa bağlantıları okuma sütununun içinde duruyor;
   oradaki 16rem'lik asgari genişlik tek sütuna düşürüyordu. */
.prose .rel-grid {
  width: 100%; padding-bottom: 0;
  grid-template-columns: repeat(auto-fit, minmax(12.5rem, 1fr));
}

/* ------------------------------------------------------------ sorular */

.faq { margin-top: 3.25rem; }
.faq > h2 { margin-top: 0; }
.qa {
  padding: 1.35rem 0; border-top: 1px solid var(--rule-soft);
}
.qa:last-child { border-bottom: 1px solid var(--rule-soft); }
.qa h3 {
  font-family: var(--serif); font-size: 1.16rem; font-weight: 500;
  letter-spacing: -.014em; margin: 0 0 .55rem;
}
.qa p { margin: 0; font-size: .97rem; }

/* Bölüm sayfasının giriş metni: kart ızgarasından önce, dolaşım sayfasını
   kendi başına anlamlı kılan kadar. */
.section-intro { padding-bottom: 2.5rem; }
.section-intro p:last-child { margin-bottom: 0; }